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Heredity and Level of Affectedness with CdLS

What are the possibilities for an individual with CdLS to have a child with CdLS? If they do, will that child most likely show a similar level of affectedness?

Individuals with CdLS are likely to be the more mildly affected if they are able to achieve reproduction. This type is thought to be due to a dominant gene. This means that the individual with CdLS has a 50% chance, in each reproductive event, to have a child with CdLS. The child may be similarly affected or more severely affected than the parent. 

LJ (4-10-01)

Most individuals with CdLS should be considered to be fertile, unless a male with undescended testicles.  Females need to be protected if in an unsupervised situation.

TK 7-13-10



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